Semaphorin 3A: A Potential Target for Low Back Pain

Semaphorin 3A: A Potential Target for Low Back Pain

Low back pain is a common disorder. Pathological innervation and intervertebral disc degeneration are two major factors associated with this disease. Semaphorin 3A, originally known for its potent inhibiting effect on axonal outgrowth, is recently found to correlate with disease activity and histological features in some skeletal disorders. Based on its effects on innervation and vascularizatio...

Semaphorin 3A, a potential immune regulator in Familial Mediterranean Fever

OBJECTIVES Semaphorin 3A (sema3A) plays a regulatory role in immune responses with effects on both T and B regulatory cells. Familial Mediterranean fever (FMF) is an autoinflammatory disease, yet a possible role for regulatory T and B cells has been described. METHODS 17 FMF patients during attack and then in remission, 8 FMF patients with smoldering disease and 12 healthy controls were enrol...

A comparative study of trunk proprioception between patients with chronic non-specific low back pain and discopathic low back pain

Introduction: Low back pain is one of the most common disorders in modern society. Disturbed properioception can be a possible cause of low back pain and can cause recurrence of low back pain. Previous studies have shown that low back pain reduces proprioception due to instability in the low back. Since the degenerative process of disc herniation is one of the important factors in exacerbating ...

Repeated Imaging for Diagnosis of Low Back Pain

Effects of acupressure on low back pain

Low Bock Pain is a very common condition; as about 80% of people experience it throughout their life. Low Back Pain has negative effects on different aspects of the clients’ lives. The objective of the research is conducted to evaluate the effect of acupressure on Low Back Pain and decline amount medication. Ninety patients were selected by convenience sampling and then randomly divided into th...